I tweet regularly at owensonline, astronomy2009uk, and britastro.
I have plentiful experience in running a Twitter feed, as well as running events on Twitter. See, for example, the Twitter Meteorwatch, run in collaboration with Adrian West at Virtual Astro, and during which 20,000 people looked up and saw a shooting star for the first time!
If you want a Twitter feed for your business, event, or organisation, please get in touch to discuss how we can make Twitter work for you.